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Dorso-ventral heterogeneity in tracheal basal stem cells

Authors
  • Tadokoro, Tomomi1, 2, 3
  • Tanaka, Keisuke4
  • Osakabe, Shun1
  • Kato, Mimoko1
  • Kobayashi, Hisato4, 5
  • Hogan, Brigid L. M.2
  • Taniguchi, Hideki1, 3
  • 1 Yokohama City University Graduate School of Medicine, Department of Regenerative Medicine, Yokohama, Kanagawa 236-0004 , (Japan)
  • 2 Duke University School of Medicine, Department of Cell Biology, Durham, NC 27707
  • 3 Center for Stem Cell Biology and Regenerative Medicine, Institute of Medical Science, University of Tokyo, Division of Regenerative Medicine, Minato, Tokyo 108-8639 , (Japan)
  • 4 NODAI Genome Research Center, Tokyo University of Agriculture, Setagaya, Tokyo 156-8502 , (Japan)
  • 5 Nara Medical University, Department of Embryology, Kashihara, Nara 634-8521 , (Japan)
Type
Published Article
Journal
Biology Open
Publisher
The Company of Biologists
Publication Date
Sep 14, 2021
Volume
10
Issue
9
Identifiers
DOI: 10.1242/bio.058676
PMID: 34396394
PMCID: PMC8467549
Source
PubMed Central
Keywords
Disciplines
  • Research Article
License
Unknown

Abstract

Summary: Spatial difference of tracheal epithelium, especially focused on the heterogeneity of basal stem cells, is elucidated by lineage tracing in vivo , histological analysis, tracheosphere culture, and gene ontology analysis.

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