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Is donating blood for the faint of heart? a systematic review of predictors of syncope in whole blood donors.

Authors
  • Donald, Scott J1
  • McIntyre, William F2
  • Dingwall, Orvie3
  • Hiebert, Brett4
  • Ponnampalam, Arjuna5
  • Seifer, Colette M1
  • 1 Section of Cardiology, Department of Internal Medicine, Max Rady College of Medicine, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, Canada. , (Canada)
  • 2 McMaster University, Hamilton, Ontario, Canada. , (Canada)
  • 3 Neil John Maclean Health Sciences Library, University of Manitoba, Winnipeg, Canada. , (Canada)
  • 4 Cardiac Sciences Program, St Boniface Hospital, Winnipeg, Canada. , (Canada)
  • 5 Section of Hematology, Department of Internal Medicine, Max Rady College of Medicine, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, Manitoba, Canada. , (Canada)
Type
Published Article
Journal
Transfusion
Publication Date
Sep 01, 2019
Volume
59
Issue
9
Pages
2865–2869
Identifiers
DOI: 10.1111/trf.15442
PMID: 31276216
Source
Medline
Language
English
License
Unknown

Abstract

Adverse events during donation negatively impact the likelihood of subsequent donation. Syncope is a possible complication of blood donation in healthy individuals. This systematic review aims to identify risk factors for syncope in healthy blood donors. Medline, Embase, Cochrane, CINAHL, Web of Science, Transfusion Evidence Library, and PubMed libraries up to November 2016 were searched. Inclusion criteria were observational and interventional trials, case series including more than 10 participants, randomized controlled trials, and clinical trials. Papers required data pertaining to syncopal events separate from presyncope for inclusion. Incomplete text or non-English language versions were excluded. Papers were evaluated using the CHARMS 2014 checklist. From 3316 papers, 1297 unique citations were identified, and 11 were selected for data extraction. Sex, estimated blood volume, age, donor status, blood pressure, heart rate, weight, previous reaction, caffeine, sleep, and donation site were identified as risk factors for syncope during blood donation. Possible risk factors for syncope in healthy blood donors have been identified that could allow for improved screening prior to donation and potential reduction in donor attrition due to negative experiences. © 2019 AABB.

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