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Does successful treatment of overactive bladder improve co-morbidities in patients with nocturia?

Authors
  • Chin, Kai Sin1
  • Rose, Georgie E1
  • Ervin, Claire F2
  • Ong, Tee Juan1
  • Whishaw, David M1
  • Bower, Wendy F1, 3
  • 1 Department of Medicine and Aged Care, The Royal Melbourne Hospital, Melbourne, Victoria, Australia. , (Australia)
  • 2 Department of Sub-Acute Care Services, The Royal Melbourne Hospital, Melbourne, Victoria, Australia. , (Australia)
  • 3 Faculty of Medicine, Dentistry and Health Services, The University of Melbourne, Melbourne, Victoria, Australia. , (Australia)
Type
Published Article
Journal
Australasian journal on ageing
Publication Date
Dec 01, 2019
Volume
38
Issue
4
Pages
242–248
Identifiers
DOI: 10.1111/ajag.12644
PMID: 30865375
Source
Medline
Keywords
Language
English
License
Unknown

Abstract

To investigate whether treatment of overactive bladder (OAB), one comorbidity of nocturia, could reduce waking to void and improve other co-existing symptoms. A prospective cohort study was conducted at Royal Melbourne Hospital. Participants received 12 weeks of standard treatment, including lifestyle interventions and pharmacotherapy. Outcome measures were nocturia episodes, severity of urinary urgency/incontinence, sleep quality, daytime somnolence, anxiety and depression scores, quality of life and change in blood pressure. Twenty participants completed the study. Nocturia frequency improved by one void per night. Overactive Bladder Symptom Score, sleep quality, first uninterrupted sleep time and systolic blood pressures improved. There were no significant changes in daytime somnolence, mood or quality of life. In this pilot study, nocturia and other co-morbid dysfunctions appeared to improve when the severity of OAB was reduced. Treatment of OAB co-morbid with nocturia reduces urinary symptoms and may improve sleep parameters and positively impact return to health. © 2019 AJA Inc.

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