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Does PET/CT give incremental staging information in cancer oesophagus compared to CECT?

  • Gamal, Gihan Hassan1
  • 1 October 6 University, Giza, Egypt , Giza (Egypt)
Published Article
Egyptian Journal of Radiology and Nuclear Medicine
Springer Berlin Heidelberg
Publication Date
Dec 30, 2019
DOI: 10.1186/s43055-019-0114-8
Springer Nature


BackgroundThe purposes of this study were to evaluate the efficiency of (18F-FDG) positron emission tomography/computed tomography (PET/CT) in diagnosing and staging of esophageal cancer and to compare the results with that of contrast-enhanced computed tomography (CECT) using the histopathological diagnosis as a gold standard.ResultsThis is a prospective study of 19 patients from June 2017 to June 2019 (17 male, 2 female) with mean age of 68 years with newly clinical, and pathologically proven esophageal carcinoma were included in this study, all patients underwent CECT followed by PET/CT imaging as an attempt of proper staging of carcinoma.It was found that PET/CT has changed the stage group of 8 patients out of 19. Six of 8 patients were upstaged on the basis of PET/CT findings while 2 of 8 were downstaged.The statistical results of CECT in regional lymph nodes sensitivity, specificity, PPV, NPV, and accuracy were 53%, 95%, 82%, 80%, and 82% while those of PET/CT were 68%, 82%, 68%, 82%, and 79%, respectively. As regards the distant metastasis, the sensitivity, specificity, PPV, NPV, and accuracy of PET/CT were 100%, 83%, 96%, 100%, and 96% versus 73%, 100%, 100%, 50%, and 79% for CECT.ConclusionAs an important diagnostic method, FGD-PET/CT showed a great impact on initial tumor staging of the patient with esophageal cancer and on the ability to detect distant metastases missed by CECT. Thus, leading to a change in clinical management of a significant number of patients.

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