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Does antidepressant use attenuate the risk of a major depressive episode in pregnancy?

Authors
  • Yonkers, Kimberly A
  • Gotman, Nathan
  • Smith, Megan V
  • Forray, Ariadna
  • Belanger, Kathleen
  • Brunetto, Wendy L
  • Lin, Haiqun
  • Burkman, Ronald T
  • Zelop, Carolyn M
  • Lockwood, Charles J
Type
Published Article
Journal
Epidemiology
Publisher
Ovid Technologies (Wolters Kluwer) - Lippincott Williams & Wilkins
Publication Date
Nov 01, 2011
Volume
22
Issue
6
Pages
848–854
Identifiers
DOI: 10.1097/EDE.0b013e3182306847
PMID: 21900825
Source
Medline
License
Unknown

Abstract

Failure to use or discontinuation of antidepressants in pregnancy did not have a strong effect on the development of a major depressive episode. Women with 4 or more episodes before pregnancy were at high risk of a major depressive episode, independent of antidepressant use. Black and Hispanic women also were at high risk of a major depressive episode, but it is possible that this effect is attributable to unmeasured factors.

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