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DNA-graphene interactions during translocation through nanogaps.

Authors
  • Patel, Hiral N1
  • Carroll, Ian1
  • Lopez, Rodolfo Jr1
  • Sankararaman, Sandeep1
  • Etienne, Charles1
  • Kodigala, Subba Ramaiah1
  • Paul, Mark R2
  • Postma, Henk W Ch1
  • 1 Department of Physics and Astronomy, California State University Northridge, Northridge, California, United States of America. , (United States)
  • 2 Department of Mechanical Engineering, Virginia Polytechnic Institute and State University, Blacksburg, Virginia, United States of America. , (United States)
Type
Published Article
Journal
PLoS ONE
Publisher
Public Library of Science
Publication Date
Jan 01, 2017
Volume
12
Issue
2
Identifiers
DOI: 10.1371/journal.pone.0171505
PMID: 28158244
Source
Medline
License
Unknown

Abstract

We study how double-stranded DNA translocates through graphene nanogaps. Nanogaps are fabricated with a novel capillary-force induced graphene nanogap formation technique. DNA translocation signatures for nanogaps are qualitatively different from those obtained with circular nanopores, owing to the distinct shape of the gaps discussed here. Translocation time and conductance values vary by ∼ 100%, which we suggest are caused by local gap width variations. We also observe exponentially relaxing current traces. We suggest that slow relaxation of the graphene membrane following DNA translocation may be responsible. We conclude that DNA-graphene interactions are important, and need to be considered for graphene-nanogap based devices. This work further opens up new avenues for direct read of single molecule activitities, and possibly sequencing.

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