Affordable Access

deepdyve-link deepdyve-link
Publisher Website

DNA polyfluorophores for real-time multicolor tracking of dynamic biological systems.

Authors
  • Wang, Shenliang
  • Guo, Jia
  • Ono, Toshikazu
  • Kool, Eric T
Type
Published Article
Journal
Angewandte Chemie International Edition in English
Publisher
Wiley (John Wiley & Sons)
Publication Date
Jul 16, 2012
Volume
51
Issue
29
Pages
7176–7180
Identifiers
DOI: 10.1002/anie.201201928
PMID: 22684777
Source
Medline
License
Unknown

Abstract

Dye-ing to live: Spectral limitations of common organic dyes make it difficult or impossible to visualize and follow multiple biological components in rapidly moving systems. The development of a multispectral set of improved DNA-scaffolded fluorophores is described. Their use in multicolor cellular imaging (see scheme) and in tracking of biological motions on the subsecond timescale is demonstrated.

Report this publication

Statistics

Seen <100 times