Affordable Access

DNA fragmentation in the CA2 sector of gerbil hippocampus following transient forebrain ischemia.

Authors
  • Iwai, T
  • Niwa, M
  • Hara, A
  • Mori, H
  • Uematsu, T
  • Sakai, N
Type
Published Article
Journal
Brain Research
Publisher
Elsevier
Publication Date
Feb 28, 2000
Volume
857
Issue
1-2
Pages
275–278
Identifiers
PMID: 10700576
Source
Medline
License
Unknown

Abstract

It has been reported that following transient forebrain ischemia in the gerbil, "delayed neuronal death" and "reactive change" occur in hippocampal CA1 and CA2 sectors, respectively. In the present study, using the gerbil transient forebrain ischemia model, we examined brain sections after various recirculation periods and demonstrated, employing the in situ nick-end labeling (TUNEL) method, a nuclear DNA fragmentation in the damaged CA2 neurons.

Report this publication

Statistics

Seen <100 times