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DNA damage induced by asbestos in the presence of hydrogen peroxide.

Authors
  • Kasai, H
  • Nishimura, S
Type
Published Article
Journal
Gan
Publication Date
Oct 01, 1984
Volume
75
Issue
10
Pages
841–844
Identifiers
PMID: 6510633
Source
Medline
Language
English
License
Unknown

Abstract

Treatment of calf thymus DNA with various types of asbestos fibers in the presence of hydrogen peroxide under physiological conditions (pH 7.4, 37 degrees) resulted in the hydroxylation of the C-8 position of guanine residues. DNA strand scission was also detected after these treatments.

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