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Distribution of tissue kallikrein in the integumental blood vessel system of wild mammals.

Authors
  • Meyer, W
Type
Published Article
Journal
Cellular and molecular biology (Noisy-le-Grand, France)
Publication Date
Jan 01, 2001
Volume
47 Online Pub
Identifiers
PMID: 11936857
Source
Medline
License
Unknown

Abstract

The study demonstrates tissue kallikrein with the help of a very sensitive immunohistochemical B-SA method in smooth muscle cells and myocytes / pericytes of the wall of subepidermal arterioles and capillaries of 17 mammalian species from 6 different orders. Positive immunoreactions could also be detected in the wall of blood vessels near to and between hair follicles and skin glands. The reaction staining in subepidermal blood vessels was particularly distinct in animals with a vital epidermis that was significantly thicker than 20 microm. The results obtained are discussed with special regard to the general skin biology of the wild mammals studied, considering comparative hair coat density and normal hazards to the integument.

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