Affordable Access

[Distribution of sulfanilamides and penicillins in the blood and organs of rats after their combined administration].

Authors
  • Bobrov, V I
  • Beletskaia, G T
Type
Published Article
Journal
Antibiotiki
Publication Date
Dec 01, 1984
Volume
29
Issue
12
Pages
913–916
Identifiers
PMID: 6524894
Source
Medline
License
Unknown

Abstract

The use of benzylpenicillin and ampicillin in combination with sulfalen or sulfadimethoxine increased the levels of the penicillins and sulfalen in some organs and tissues of rats. This was accompanied by a rise in the concentration gradients of the drugs. It is concluded that the combined use of the penicillins and sulfanilamides determines their increased penetration from the blood into other organs and tissues of the host.

Report this publication

Statistics

Seen <100 times