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Distribution of the saa gene in strains of Shiga toxin-producing Escherichia coli of human and bovine origins.

Authors
  • Jenkins, Claire
  • Perry, Neil T
  • Cheasty, Tom
  • Shaw, Darren J
  • Frankel, Gad
  • Dougan, Gordon
  • Gunn, George J
  • Smith, Henry R
  • Paton, Adrienne W
  • Paton, James C
Type
Published Article
Journal
Journal of clinical microbiology
Publication Date
Apr 01, 2003
Volume
41
Issue
4
Pages
1775–1778
Identifiers
PMID: 12682185
Source
Medline
License
Unknown

Abstract

Certain strains of Shiga toxin-producing Escherichia coli (STEC) which do not have the locus of enterocyte effacement pathogenicity island carry the STEC autoagglutinating adhesin (saa) gene. The distribution of the saa gene in STEC isolates from patients with hemolytic-uremic syndrome (HUS), patients with less severe diarrheal disease, asymptomatic individuals, and healthy cattle was examined. saa-positive strains were detected more frequently (P < 0.001) in STEC strains from bovines (32 of 56 strains) than in those from humans (8 of 91 strains). No significant association (P = 0.135) was found between the saa gene and STEC isolated from patients with HUS (6 of 46 strains) or diarrhea (2 of 29 strains) and from healthy controls (0 of 16 strains).

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