Distribution of estrogen receptor in ductal carcinoma in situ of the breast.
- Published Article
- Publication Date
Feb 01, 1993
The incidence of ER in DCIS is similar to the incidence of ER in invasive carcinoma, leading to the speculation that ER-positive invasive carcinoma originates from an ER-positive precursor lesion. Because only 60% of the cases have detectable ER and approximately 70% of positively stained ERs are expected to be functional (as in invasive carcinoma), it appears that approximately 42% of the patient population with DCIS will benefit from antiestrogen therapy.
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The corresponding record at NLM can be accessed at https://www.ncbi.nlm.nih.gov/pubmed/8381562