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Dissolution of thrombotic arterial occlusion by high intensity, low frequency ultrasound and dodecafluoropentane emulsion: an in vitro and in vivo study.

Authors
  • Nishioka, T
  • Luo, H
  • Fishbein, M C
  • Cercek, B
  • Forrester, J S
  • Kim, C J
  • Berglund, H
  • Siegel, R J
Type
Published Article
Journal
Journal of the American College of Cardiology
Publisher
Elsevier
Publication Date
Aug 01, 1997
Volume
30
Issue
2
Pages
561–568
Identifiers
PMID: 9247533
Source
Medline
License
Unknown

Abstract

1) DDFP emulsion, an echo contrast agent, significantly enhances the clot-disrupting effect of low frequency ultrasound in vitro and in an in vivo rabbit iliofemoral occlusion model. 2) This simple combination therapy has potential for clinical application in patients with thrombotic arterial occlusions.

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