Affordable Access

Disseminated T-cell lymphoma in a Brazilian porcupine (Coendou prehensilis).

Authors
  • de Araújo, Marina Rios1
  • Luppi, Marcela Miranda
  • Malta, Marcelo de Campos Cordeiro
  • Assumpção, Anna Luiza Facchetti Vinhaes
  • Langohr, Ingeborg Maria
  • Ecco, Roselene
  • 1 Veterinary School, Universidade Federal de Minas Gerais, Pampulha, Belo Horizonte, Minas Gerais 31270-901, Brazil. , (Brazil)
Type
Published Article
Journal
Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc
Publication Date
Jan 01, 2011
Volume
23
Issue
1
Pages
132–135
Identifiers
PMID: 21217044
Source
Medline
Language
English
License
Unknown

Abstract

The current study describes the clinical, gross, histopathologic, and immunohistochemical findings of a T-cell lymphoma in a captive porcupine (Coendou prehensilis), a species typically seen in the tropical forests of Brazil. At necropsy, extensive neoplastic involvement was observed in the cervical lymph nodes, with extension into the salivary gland. The spleen was mildly enlarged, and neoplastic nodules were grossly evident in the liver and right kidney. Histologically, sheets of large and markedly pleomorphic round cells were observed in the cervical lymph nodes, lung, liver, spleen, and kidney. The neoplastic cells were positive for cluster of differentiation (CD)3 and negative for CD79a by immunohistochemistry.

Report this publication

Statistics

Seen <100 times