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Disseminated form of the Kaposi sarcoma in HIV-negative patient associated with Hodgkin’s lymphoma

Authors
  • Tutaeva, V V1
  • Bobin, A N1
  • Ovsiannikova, M R1
  • Bulgakova, M V2
  • Kuchma, Y M1
  • Kryukov, E V3
  • Rukavitsyn, O A1
  • 1 Main Military Clinical Hospital named after N.N. Burdenko, Russia , (Russia)
  • 2 Department of Radiology
  • 3 The Main Military Clinical Hospital named after N.N. Burdenko
Type
Published Article
Journal
Oxford Medical Case Reports
Publisher
Oxford University Press
Publication Date
Sep 22, 2020
Volume
2020
Issue
9
Identifiers
DOI: 10.1093/omcr/omaa069
PMID: 32995025
PMCID: PMC7507874
Source
PubMed Central
Keywords
License
Unknown

Abstract

We report a case of a 35-year-old, non-HIV-infected male diagnosed simultaneously with a disseminated form of Kaposi’s sarcoma (KS; skin, stomach and colon are involved) and Hodgkin’s lymphoma. There is no sign of changes in the immune status, but three herpes viruses were detected in the patient’s blood (EBV, HHV6 and HHV8). He received ABVD chemotherapy and achieved complete metabolic remission for Hodgkin’s lymphoma. Moreover, the signs of the disseminated KS were resolved. Our observations indicate that a combination of distinct types of viruses may play an important role in triggering the development of angio- and lymphoproliferative disorders in the same person. In addition, treatment with chemotherapy cycles, which included doxorubicin and vinblastine, led to the stable remission of both diseases.

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