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Disparate associations of a functional promoter polymorphism in PCK1 with carotid wall ultrasound traits.

Authors
  • Hegele, Robert A
  • Al-Shali, Khalid Z
  • House, Andrew A
  • Hanley, Anthony J G
  • Harris, Stewart B
  • Mamakeesick, Mary
  • Fenster, Aaron
  • Zinman, Bernard
  • Cao, Henian
  • Spence, J David
Type
Published Article
Journal
Stroke
Publisher
Ovid Technologies Wolters Kluwer -American Heart Association
Publication Date
Dec 01, 2005
Volume
36
Issue
12
Pages
2566–2570
Identifiers
PMID: 16282543
Source
Medline
License
Unknown

Abstract

The findings connect the key enzyme in gluconeogenesis with atherosclerosis. The meaning of the opposing associations of PCK1 genotype with IMT and TPV is unclear; more work is required to confirm whether these might be distinct quantitative traits with different biological determinants.

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