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The Disillusioned Comfort with COVID-19 and the Potential of Convalescent Plasma and Cell Therapy.

Authors
  • Borlongan, Mia C1
  • Borlongan, Maximillian C2
  • Sanberg, Paul R3
  • 1 1438University of California Berkeley, Berkeley, CA, USA.
  • 2 7831Tampa Preparatory School, Tampa, FL, USA.
  • 3 7831University of South Florida, Tampa, FL, USA.
Type
Published Article
Journal
Cell Transplantation
Publisher
SAGE Publications
Publication Date
Jan 01, 2020
Volume
29
Identifiers
DOI: 10.1177/0963689720940719
PMID: 32841042
Source
Medline
Keywords
Language
English
License
Unknown

Abstract

Coronavirus disease 2019 or COVID-19 is highly infectious, which can lead to acute and chronic debilitating symptoms, as well as mortality. The advent of safe and effective vaccines or antiviral drugs remains distant in the future. Practical public health measures, such as social distancing, hand washing, and wearing a face mask, are the current recommended guidelines by the Centers for Disease Control and Prevention for limiting the spread of the virus. Weakened immune system and aberrant inflammation represent a major pathological symptom of COVID-19 patients. Based on the unique immunomodulatory properties of both convalescent plasma and stem cells, we discuss here their potential use for treating COVID-19.

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