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Discovery and validation of 3 novel DNA methylation markers of prostate cancer prognosis.

Authors
  • Cottrell, Susan
  • Jung, Klaus
  • Kristiansen, Glen
  • Eltze, Elke
  • Semjonow, Axel
  • Ittmann, Michael
  • Hartmann, Arndt
  • Stamey, Thomas
  • Haefliger, Carolina
  • Weiss, Gunter
Type
Published Article
Journal
The Journal of Urology
Publisher
Elsevier
Publication Date
May 01, 2007
Volume
177
Issue
5
Pages
1753–1758
Identifiers
PMID: 17437806
Source
Medline
License
Unknown

Abstract

We report that methylation of the 3 novel markers GPR7, ABHD9 and Chr3-EST is significantly associated with prostate cancer prognosis. Incorporation of these methylation markers into clinical practice will result in more accurate prediction of which patients are likely to experience PSA recurrence.

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