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Discovery and development of pyrethroid insecticides.

Authors
  • Matsuo, Noritada1, 2
  • 1 School of Science and Technology, Kwansei Gakuin University.
  • 2 SC Environmental Science Co., Ltd.
Type
Published Article
Journal
Proceedings of the Japan Academy. Series B, Physical and biological sciences
Publication Date
Jan 01, 2019
Volume
95
Issue
7
Pages
378–400
Identifiers
DOI: 10.2183/pjab.95.027
PMID: 31406060
Source
Medline
Keywords
Language
English
License
Unknown

Abstract

Pyrethroid insecticides contain natural pyrethrins extracted from pyrethrum flowers, and their synthetic derivatives, pyrethroids. The present article provides an overview of the structure of natural pyrethrins, and the discovery and development of pyrethroids with an emphasis on the background of selected compounds. The stereochemical relationships among pyrethroid secondary alcohols, and toxicologic and environmental effects of pyrethroids are also discussed. Finally, the pyrethroid resistance of mosquitoes and future aspects of pyrethroids are addressed.

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