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Direct thrombin inhibitors: alternatives to heparin.

Authors
  • Mureebe, Leila
Type
Published Article
Journal
Vascular
Publication Date
Jan 01, 2007
Volume
15
Issue
6
Pages
372–375
Identifiers
PMID: 18053423
Source
Medline
License
Unknown

Abstract

After more than 70 years of effective clinical use, heparin remains the most common anticoagulant in use and one of the most commonly prescribed drugs to hospitalized patients. However, the biologic variability and immunogenicity limit its utility. With increasing volumes of vascular intervention and an aging population, an increase in the need for anticoagulation can be anticipated. This article reviews current viable options and barriers to the use of heparin.

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