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Dimethyl sulfoxide inhibits killing of Staphylococcus aureus by polymorphonuclear leukocytes.

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Abstract

Increasing concentrations of the highly permeable, hydroxyl radical scavenger dimethyl sulfoxide progressively decreased killing of Staphylococcus aureus 502A by human polymorphonuclear leukocytes; methane, a product of the reaction of the hydroxyl radical with dimethyl sulfoxide, was generated in the process.

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