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Differential gene and protein expression in primary breast malignancies and their lymph node metastases as revealed by combined cDNA microarray and tissue microarray analysis.

Authors
Type
Published Article
Journal
Cancer
Publication Date
Volume
100
Issue
6
Pages
1110–1122
Identifiers
PMID: 15022276
Source
Medline
License
Unknown

Abstract

The results of the current study suggest that extracellular matrix protein expression and nuclear gene expression are associated via a negative-feedback regulatory mechanism. Therefore, gene expression profiling and tissue array validation should be combined to elucidate molecular events associated with the metastatic process.

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