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Differential effects of glucagon on induction of rat liver glucose-6-phosphate dehydrogenase by liver injury and dietary change.

Authors
  • Watanabe, A
  • Takesue, A
  • Taketa, K
Type
Published Article
Journal
Enzyme
Publication Date
Jan 01, 1976
Volume
21
Issue
3
Pages
193–199
Identifiers
PMID: 1278134
Source
Medline
License
Unknown

Abstract

Glucagon effectively prevented the increase in glucose-6-phosphate dehodrogenase activity of rat liver following the administration of a glucose-casein mixture without altering the amount of the diet consumed. However, the increase of the enzyme level in carbon tetrachloride-injured rat liver was virtually insensitive to glucagon. The results obtained gave further evidence for the difference between these two induction mechanisms of glucose-6-phosphate dehydrogenase.

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