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Differential diagnosis of schistosomiasis mekongi and trichinellosis in human.

Authors
  • Ittiprasert, W
  • Butraporn, P
  • Kitikoon, V
  • Klongkamnuankarn, K
  • Pholsena, K
  • Vanisaveth, V
  • Sakolvaree, Y
  • Chongsa-nguan, M
  • Tapchaisri, P
  • Mahakunkijcharoen, Y
  • Kurazono, H
  • Hayashi, H
  • Chaicumpa, W
Type
Published Article
Journal
Parasitology international
Publication Date
Sep 01, 2000
Volume
49
Issue
3
Pages
209–218
Identifiers
PMID: 11426576
Source
Medline
License
Unknown

Abstract

An indirect (plate) ELISA and, a more convenient version, a dot-blot (membrane) ELISA have been developed using haemocyanin of a mollusk, Megathura crenulata, i.e. keyhole limpet haemocyanin (KLH) and purified, specific antigen of Trichinella spiralis (APTsAg) obtained from a monoclonal antibody-affinity column chromatography, for differential diagnosis of schistosomiasis mekongi and trichinellosis. Serum samples of patients with parasitologically confirmed trichinellosis were reactive to both antigens in both versions of ELISA while sera of patients with schistosomiasis mekongi were positive only to the KLH. Both ELISA were negative when used to test sera of normal controls and patients with gnathostomiasis, paragonimiasis and opisthorchiasis.

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