Affordable Access

[The different responses to anoxia in cultured CA1 and DG neurons from newborn rats].

Authors
Type
Published Article
Journal
Sheng li xue bao : [Acta physiologica Sinica]
Publication Date
Volume
50
Issue
1
Pages
61–66
Identifiers
PMID: 11324519
Source
Medline
License
Unknown

Abstract

Tissue culture from hippocampal CA1 or dentate gyrus (DG) region was established on the basis of previous neuronal culture technique. The viability, intracellular calcium concentration and brain-derived neurotrophic factor (BDNF) mRNA expression of the two kinds of neurons after anoxia were observed in the counting in the confocal microscopic field and in situ hybridization. It is found that DG neurons are not only more resistant to anoxia, but also have a stronger ability to keep calcium homeostasis and to express BDNF mRNA than CA1 neurons.

Statistics

Seen <100 times