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Differences in ischaemia tolerance between hypertrophied hearts of adult and aged spontaneously hypertensive rats.

Authors
  • Snoeckx, L H
  • van der Vusse, G J
  • Coumans, W A
  • Willemsen, P H
  • Reneman, R S
Type
Published Article
Journal
Cardiovascular research
Publication Date
May 01, 1993
Volume
27
Issue
5
Pages
874–881
Identifiers
PMID: 8348587
Source
Medline
License
Unknown

Abstract

The aged hypertrophied heart shows a higher vulnerability to ischaemic damage than the adult hypertrophied heart. This phenomenon is associated with subendocardial underperfusion, increased membrane damage and inadequate recovery of creatine phosphate levels.

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