These results indicate that the microglial TNF-α p55 pathway played a more important role than the TNF-α p75 pathway in the pathogenesis of peripheral nerve injury pain. This suggests that future studies seeking to clarify neuropathic pain should target TNF-α and p55 receptors in microglia.
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The corresponding record at NLM can be accessed at https://www.ncbi.nlm.nih.gov/pubmed/22652595