Affordable Access

Difference of auditory brainstem responses by stimulating to round and oval window in animal experiments.

Authors
  • Lee, Jyung Hyun1
  • Park, Hyo Soon2
  • Wei, Qun3
  • Kim, Myoung Nam1
  • Cho, Jin-Ho4
  • 1 a Department of Biomedical Engineering , School of Medicine, Kyungpook National University , Daegu , Korea. , (North Korea)
  • 2 b Graduate School of Electronics Engineering , Graduate school, Kungpook National University , Daegu , Korea. , (North Korea)
  • 3 c Department of Biomedical Engineering , School of Medicine, Keimyung University , Daegu , Korea. , (North Korea)
  • 4 d School of Electronics Engineering , College of IT Engineering, Kyungpook National University , Daegu , Korea. , (North Korea)
Type
Published Article
Journal
Bioengineered
Publisher
Landes Bioscience
Publication Date
Jan 02, 2017
Volume
8
Issue
1
Pages
8–13
Identifiers
PMID: 27689303
Source
Medline
Keywords
Language
English
License
Unknown

Abstract

ABSTACT To ensure the safety and efficacy of implantable hearing aids, animal experiments are an essential developmental procedure, in particular, auditory brainstem responses (ABRs) can be used to verify the objective effectiveness of implantable hearing aids. This study measured and compared the ABRs generated when applying the same vibration stimuli to an oval window and round window. The ABRs were measured using a TDT system 3 (TDT, USA), while the vibration stimuli were applied to a round window and oval window in 4 guinea pigs using a piezo-electric transducer with a proper contact tip. A paired t-test was used to determine any differences between the ABR amplitudes when applying the stimulation to an oval window and round window. The paired t-test revealed a significant difference between the ABR amplitudes generated by the round and oval window stimulation (t = 10.079, α < .0001). Therefore, the results confirmed that the biological response to round window stimulation was not the same as that to oval window stimulation.

Report this publication

Statistics

Seen <100 times