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Diaspirin cross-linked hemoglobin improves mucosal perfusion in the ileum of septic rats.

Authors
  • Sielenkämper, A W
  • Eichelbrönner, O
  • Martin, C M
  • Madorin, S W
  • Chin-Yee, I H
  • Sibbald, W J
Type
Published Article
Journal
Critical Care Medicine
Publisher
Ovid Technologies (Wolters Kluwer) - Lippincott Williams & Wilkins
Publication Date
Mar 01, 2000
Volume
28
Issue
3
Pages
782–787
Identifiers
PMID: 10752830
Source
Medline
License
Unknown

Abstract

Both DCLHb and pentastarch infusion improved microcirculatory perfusion in the ileum of septic rats. In addition, DCLHb also exhibited vasopressor properties, which in combination with improved perfusion may be particularly useful in the treatment of sepsis.

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