The nature of industrial manufacturing processes and the continuous need to adapt production systems to new demands require tools to support workers during transitions to new processes. At the early stage of transitions, human error rate is often high and the impact in quality and production loss can be significant. Over the past years, eXtended Reality (XR) technologies (such as virtual, augmented, immersive, and mixed reality) have become a popular approach to enhance operators&rsquo / capabilities in the Industry 4.0 paradigm. The purpose of this research is to explore the usability of dialogue-based XR enhancement to ease the cognitive burden associated with manufacturing tasks, through the augmentation of linked multi-modal information available to support operators. The proposed Interactive XR architecture, using the Spoken Dialogue Systems&rsquo / modular and user-centred architecture as a basis, was tested in two use case scenarios: the maintenance of a robotic gripper and as a shop-floor assistant for electric panel assembly. In both cases, we have confirmed a high user acceptance rate with an efficient knowledge communication and distribution even for operators without prior experience or with cognitive impairments, therefore demonstrating the suitability of the solution for assisting human workers in industrial manufacturing processes. The results endorse an initial validation of the Interactive XR architecture to achieve a multi-device and user-friendly experience to solve industrial processes, which is flexible enough to encompass multiple tasks.