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Diagnostic Value of CRP, Procalcitonin, and Ferritin Levels in Cerebrospinal Fluid of Children with Meningitis.

Authors
  • Shokrollahi, Mohammad R1
  • Shabanzadeh, Khalil2
  • Noorbakhsh, Samileh2
  • Tabatabaei, Azardokht2
  • Movahedi, Zahra1
  • Shamshiri, Ahmad R3
  • 1 Research Center of Pediatric Infectious Diseases, Qom University of Medical Sciences and Health services, Qom, Iran. , (Iran)
  • 2 Research Center of Pediatric Infectious Diseases, Iran University of Medical science, Tehran, Iran. , (Iran)
  • 3 Dental Research Center, Dentistry Research Institute, Department of Community Oral Health, School of Dentistry, Tehran University of Medical Sciences, Tehran, Iran. , (Iran)
Type
Published Article
Journal
Central nervous system agents in medicinal chemistry
Publication Date
Jan 26, 2018
Volume
18
Issue
1
Pages
58–62
Identifiers
DOI: 10.2174/1871524916666160302103223
PMID: 26931764
Source
Medline
Keywords
License
Unknown

Abstract

CSF of children with bacterial meningitis contains higher levels of inflammatory mediators including Procalcitonin, Ferritin, and CRP, compared to aseptic meningitis The biomarkers provided high sensitivity (especially PCT) and specificity (especially CRP). Using these complementary biomarkers would be useful for early diagnosis of bacterial meningitis and selection of appropriate treatment.

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