Tubular structures of tumor cells and the presence of stromal fragments in breast FNA are significant indicators of stromal invasion. However, the low occurrence rate of tubular structures (24% in this series) in IDC and the low specificity of stromal fragments limit their utility in separating IDC from DCIS. Nonetheless, if present, tubular structures in conjunction with stromal fragments can be used to evaluate stromal invasion in patients whose disease is being managed surgically.
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This record was last updated on 07/02/2016 and may not reflect the most current and accurate biomedical/scientific data available from NLM.
The corresponding record at NLM can be accessed at https://www.ncbi.nlm.nih.gov/pubmed/9678734