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Diagnosis and classification of rheumatoid arthritis

Authors
  • Kourilovitch, Maria
  • Galarza-Maldonado, Claudio
  • Ortiz-Prado, Esteban1, 2, 1, 3, 4, 5
  • 1 State University
  • 2 Center of Translational Medicine
  • 3 UNERA (Unit of Rheumatic Disease and Autoimmunity)
  • 4 Medical Corporation Mount Sinai
  • 5 Universidad de las Américas (UDLA)
Type
Published Article
Journal
Journal of Autoimmunity
Publisher
Elsevier BV
Publication Date
Jan 01, 2014
Accepted Date
Nov 13, 2013
Volume
48-49
Pages
26–30
Identifiers
DOI: 10.1016/j.jaut.2014.01.027
Source
Elsevier
Keywords
License
Unknown

Abstract

Rheumatoid arthritis (RA) is a systemic chronic inflammatory disease of unclear etiology that is manifested in by a progressive and destructive polyarthritis in association with serological evidence of autoreactivity. It diagnosis is based on the classification criteria that involves four parameters: joint involvement, serology (rheumatoid factor and anti-cyclic citrullinated peptide -anti-CCP), levels of acute phase reactants and the duration of the symptoms Aletaha, et al. [1]. This classification simplify the categorization of the patients on with early RA, however, the diagnosis requires highly trained specialist who are able to differentiate early symptoms of RA from other pathology.

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