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Diabetes, markers of brain pathology and cognitive function: the Age, Gene/Environment Susceptibility-Reykjavik Study.

Authors
  • 1
  • 1 Laboratory of Epidemiology and Population Sciences, National Institute on Aging, National Institutes of Health, Bethesda, MD; Aging Research Center, Department of Neurobiology, Care Sciences, and Society, Karolinska Institutet-Stockholm University, Stockholm, Sweden. , (Sweden)
Type
Published Article
Journal
Annals of Neurology
1531-8249
Publisher
Wiley Blackwell (John Wiley & Sons)
Publication Date
Volume
75
Issue
1
Pages
138–146
Identifiers
DOI: 10.1002/ana.24063
PMID: 24243491
Source
Medline
License
Unknown

Abstract

Diabetes is associated with poor performance on cognitive tests of information-processing speed and executive function. The association is largely mediated by markers of both neurodegeneration and cerebrovascular disease. Older people with diabetes should be monitored for cognitive problems and brain lesions.

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