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Dermatomyositis sine myositis and antisynthetase syndrome

Authors
Publisher
Elsevier SAS
Publication Date
Volume
69
Issue
1
Identifiers
DOI: 10.1016/s1297-319x(01)00345-1
Keywords
  • Amyopathic Dermatomyositis
  • Dermatomyositis Sine Myositis
Disciplines
  • Biology
  • Medicine

Abstract

Abstract We describe a 66-year-old woman with cutaneous lesions typical of classic dermatomyositis, clinical evidence of antisynthetase syndrome (arthritis, Raynaud’s phenomenon, mechanic’s hands and interstitial lung disease with anti-Jo-1 autoantibody) and lack of muscle disease after a full muscle evaluation that included clinical, enzymatic, electromyographic, magnetic resonance imaging and histological studies. The patient did not develop myositis after 9 years of clinical disease. The association of dermatomyositis sine myositis with antisynthetase antibodies suggests that the characteristic skin lesions are closely linked with dermatomyositis on the basis of the similar clinical and serological features of both dermatomyositis sine myositis and classic dermatomyositis.

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