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Isomers of neplanocin A and 2′-deoxyneplanocin A possessing a C-1′/C-6′ double bond

Authors
Journal
Tetrahedron Letters
0040-4039
Publisher
Elsevier
Publication Date
Volume
46
Issue
11
Identifiers
DOI: 10.1016/j.tetlet.2005.01.061
Keywords
  • Carbocyclic Nucleosides
  • Neplanocin Analogs
  • Epoxide Ring Opening
  • Antiviral

Abstract

Abstract Missing among the unsaturated carbocyclic nucleosides is the 1′,6′-double bond isomer of neplanocin A. A practical synthesis of this compound and its 2′-deoxy derivative is reported from readily accessible cyclopentenols.

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