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Tangential excision of burns: Studies on the metabolic activity of the recipient areas for skin grafts

Authors
Journal
British Journal of Plastic Surgery
0007-1226
Publisher
Elsevier
Publication Date
Volume
26
Issue
2
Identifiers
DOI: 10.1016/s0007-1226(73)80001-3

Abstract

Summary Investigations concerning the respiratory activity, sulphated mucopolysaccharide and collagen biosynthesis were made using micro-techniques on samples of fresh tissue tangentially excised from suitable burns before grafting. It was found that the layer of tissue providing the graft bed following tangential excision was considerably less active than comparable tissue excised from a donor site. There appeared to be no correlation between the take or failure of skin grafts and the viability of the graft bed. Split-thickness grafts on a bed with reduced metabolic activity usually took successfully, the reasons for which are discussed.

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