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Dexamethasone protects airway epithelial cell line NCI-H292 against lipopolysaccharide induced endoplasmic reticulum stress and apoptosis.

Authors
  • Shang, Yan1
  • Wang, Fang
  • Bai, Chong
  • Huang, Yi
  • Zhao, Li-Jun
  • Yao, Xiao-Peng
  • Li, Qiang
  • Sun, Shu-Han
  • 1 Department of Respiratory Medicine, Changhai Hospital, Second Military Medical University, Shanghai 200433, China. , (China)
Type
Published Article
Journal
Chinese medical journal
Publication Date
Jan 01, 2011
Volume
124
Issue
1
Pages
38–44
Identifiers
PMID: 21362305
Source
Medline
License
Unknown

Abstract

LPS may activate ER stress through the overexpression of MUC5AC. Dexamethasone may protect human airway epithelial cells against ER stress-related apoptosis by attenuating the overload of MUC5AC.

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