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Dexamethasone decreases the transmesothelial electrical resistance of the parietal and visceral pleura.

Authors
Type
Published Article
Journal
The journal of physiological sciences : JPS
Publication Date
Volume
59
Issue
4
Pages
335–339
Identifiers
DOI: 10.1007/s12576-009-0042-x
PMID: 19462220
Source
Medline

Abstract

The effect of dexamethasone on the transmesothelial electrical resistance (R(TM)) of sheep pleura was investigated by Ussing chamber experiments. Our results show that dexamethasone decreases the R(TM) of sheep pleurae, in part by stimulation of glucocorticoid receptors. This finding may be of importance in regard to the faster resolution of corticosteroid-treated pleural effusions.

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