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Development and validation of a risk score for chronic kidney disease in HIV infection using prospective cohort data from the D:A:D study.

Authors
  • Mocroft, Amanda1
  • Lundgren, Jens D2
  • Ross, Michael3
  • Law, Matthew4
  • Reiss, Peter5
  • Kirk, Ole2
  • Smith, Colette1
  • Wentworth, Deborah6
  • Neuhaus, Jacqueline6
  • Fux, Christoph A7
  • Moranne, Olivier8
  • Morlat, Phillipe9
  • Johnson, Margaret A10
  • Ryom, Lene2
  • Joan P DeHovitz
Type
Published Article
Journal
PLoS Medicine
Publisher
Public Library of Science
Publication Date
Mar 01, 2015
Volume
12
Issue
3
Identifiers
DOI: 10.1371/journal.pmed.1001809
PMID: 25826420
Source
Medline
License
Unknown

Abstract

Both traditional and HIV-related risk factors were predictive of CKD. These factors were used to develop a risk score for CKD in HIV infection, externally validated, that has direct clinical relevance for patients and clinicians to weigh the benefits of certain antiretrovirals against the risk of CKD and to identify those at greatest risk of CKD.

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