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Development and validation of an instrument for measuring parkinsonian motor impairment: TRAPS-D.

Authors
  • de Oliveira Júnior, José Oswaldo1
  • Lopes, Rosimary Amorim2
  • de Gobbi Porto, Fabio Henrique3
  • Botelho, Ricardo Vieira4
  • 1 Central da Dor E Estereotaxia, AC Camargo Cancer Center, São Paulo, SP, Brazil. [email protected] , (Brazil)
  • 2 IAMSPE - Instituto de Assistência Médica Do Servidor Público Estadual, São Paulo, SP, Brazil. , (Brazil)
  • 3 Movement Disorders Neurosurgery Unit, Hospital Brigadeiro, São Paulo, SP, Brazil. , (Brazil)
  • 4 IAMSPE-Instituto de Assistência Médica do Servidor Público Estadual, São Paulo, SP, Brazil. , (Brazil)
Type
Published Article
Journal
Neurological Sciences
Publisher
Springer-Verlag
Publication Date
Apr 01, 2022
Volume
43
Issue
4
Pages
2519–2524
Identifiers
DOI: 10.1007/s10072-021-05533-3
PMID: 34709480
Source
Medline
Keywords
Language
English
License
Unknown

Abstract

Parkinson's disease is incurable, idiopathic, degenerative, and progressive, and affects about 1% of the elderly population. Multidisciplinary clinical treatment is the best and most adopted therapeutic option, while surgical treatment is used in less than 15% of those affected. In practice, there is a lack of reliable and validated scales for measuring motor impairment, and monitoring and screening for surgical indications. To develop and validate an instrument for measuring parkinsonian motor impairment in candidates for neurosurgical treatment. The development and validation methods followed published guidelines. The first part was the choice of domains that would make up the construct: cardinal signs of disease (tremor, rigidity (stiffness), posture/balance/gait, hypokinesia/akinesia, and speech), along with pain and dyskinesia. A multi-professional working group prepared an initial pilot instrument. Ten renowned specialists evaluated, judged, and suggested modifications to the instrument. The second phase was the evaluation of the content of each domain and the respective ability to classify commitment intensity. The third phase was the correction of the main flaws detected and new submission to the board. The instrument was applied to 41 candidates for neurosurgical treatment in two situations: with and without medication RESULTS: The final form received 100% agreement from the judges. Its average time for application was 8 min. It was very responsive (p = 0.001, Wilcoxon) in different situations (On-Off). TRASP-D is a valid instrument for measuring motor impairment in patients with Parkinson's disease who are candidates for neurosurgical treatment. It allows measurement in multiple domains with reliability and sensitivity. © 2021. Fondazione Società Italiana di Neurologia.

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