[Development of intravital bone tissue imaging and future perspectives of new lines of therapies for bone diseases.]
Department of Immunology and Cell Biology, Graduate School of Medicine and Frontier Biosciences, Osaka University, Japan.
- Published Article
- Publication Date
Jan 01, 2018
Recent advances in live imaging technology for 'seeing the unseen' phenomenon has been so enormous to revolutionize the diverse fields of biomedical sciences. We have so far pioneered to exploit the technique into the analyses of live bone tissues and made it possible to detect dynamic movements of single cells and multicellular interaction in intact bone tissues. Now that the cutting-edge techniques have been matured enough, we can also utilize this for validation of pharmacological actions in various regimens in vivo as well as for novel drug discovery for treating against bone diseases. In this brief review, I describe the overview of the studies related to intravital bone imaging and its application and contribution for future medicine in this field.
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The corresponding record at NLM can be accessed at https://www.ncbi.nlm.nih.gov/pubmed/29371480