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Development of HCC in patients receiving adefovir dipivoxil for lamivudine-resistant hepatitis B virus mutants.

Authors
  • Hosaka, Tetsuya
  • Suzuki, Fumitaka
  • Kobayashi, Masahiro
  • Hirakawa, Miharu
  • Kawamura, Yusuke
  • Yastuji, Hiromi
  • Sezaki, Hitomi
  • Akuta, Norio
  • Suzuki, Yoshiyuki
  • Saitoh, Satoshi
  • Arase, Yasuji
  • Ikeda, Kenji
  • Miyakawa, Yuzo
  • Kumada, Hiromitsu
Type
Published Article
Journal
Hepatology research : the official journal of the Japan Society of Hepatology
Publication Date
Feb 01, 2010
Volume
40
Issue
2
Pages
145–152
Identifiers
DOI: 10.1111/j.1872-034X.2009.00582.x
PMID: 19788684
Source
Medline
License
Unknown

Abstract

HCC can develop in cirrhotic patients receiving adefovir add-on lamivudine. Hence, the patients with baseline AST >/= 70 IU/L and YIDD mutants would need to be monitored closely for HCC.

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