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Development, current applications and future roles of biorelevant two-stage in vitro testing in drug development.

Authors
  • Fiolka, Tom1
  • Dressman, Jennifer1
  • 1 Department of Pharmaceutical Technology, Goethe University, Frankfurt/Main, Germany. , (Germany)
Type
Published Article
Journal
The Journal of pharmacy and pharmacology
Publication Date
Mar 01, 2018
Volume
70
Issue
3
Pages
335–348
Identifiers
DOI: 10.1111/jphp.12875
PMID: 29380369
Source
Medline
Keywords
License
Unknown

Abstract

Given the diversity among the various two-stage test methods available today, a more harmonized approach needs to be taken to optimize the use of two stage testing at different stages of drug development.

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