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Development of broad spectrum mycosporine loaded sunscreen formulation from Ulva fasciata delile

Authors
  • Bhatia, Saurabh
  • Sardana, Satish
  • Sharma, Ajay
  • Vargas De La Cruz, Celia Bertha
  • Chaugule, Bhupal
  • Khodaie, Laleh
Type
Published Article
Journal
BioMedicine
Publisher
EDP Sciences
Publication Date
Aug 27, 2019
Volume
9
Issue
3
Identifiers
DOI: 10.1051/bmdcn/2019090317
PMID: 31453798
PMCID: PMC6711319
Source
PubMed Central
Keywords
License
Green
External links

Abstract

Ba.ckground: Sunscreen formulations primarily offer protection against UV induced damages however nowadays it also maintains skin natural physiological conditions. Current global market is flooded with numerous sunscreen products which offer protection to skin against several UV induced damages. However most of these sunscreen formulations offers narrow spectrum protection against UV and also suffer from stability as well as toxicity related issues. Methods: Present work aims to isolate mycosporine amino acid (Mgy) from green alga namely Ulva fasciata (U. fasciata) and study its sunscreen potential against widely used domestic marketed formulation. Stability evaluations were also performed for almost 90 days. Results: Results demonstrated that the isolated compound, mycosporine glycine (Mgy) preserved physicochemical properties of the product and offered good stability for all formulations throughout the experimental period. Furthermore, Mgy loaded carbopol gel showed better sunscreen protection against marketed formulation in a concentration dependent manner. (7.709). Conclusion: (6.806) Novel Myg loaded gel was proved to demonstrate several quality characteristics that may unlock new prospects for the production of more efficient, safe, and economic skin-care products.

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