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Determinants of risk for venous and arterial thrombosis in primary antiphospholipid syndrome and in antiphospholipid syndrome with systemic lupus erythematosus.

Authors
  • Danowski, Adriana
  • de Azevedo, Mario Newton Leitão
  • de Souza Papi, Jose Angelo
  • Petri, Michelle
Type
Published Article
Journal
The Journal of rheumatology
Publication Date
Jun 01, 2009
Volume
36
Issue
6
Pages
1195–1199
Identifiers
DOI: 10.3899/jrheum.081194
PMID: 19447935
Source
Medline
License
Unknown

Abstract

The frequency of thrombosis and pregnancy loss is greater in APS associated with SLE than in primary APS. Risk factors differ for venous and arterial thrombosis in APS. Treatment of hypertension may be the most important intervention to reduce arterial thrombosis. Elevated triglycerides are a major associate of venous thrombosis, but the benefit of treatment is not known. Hereditary thrombophilia is an associate of venous but not arterial thrombosis, making it cost-effective to investigate only in venous thrombosis.

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