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Detection of SARS-CoV-2-specific humoral and cellular immunity in COVID-19 convalescent individuals

Authors
  • Ni, Ling1, 2
  • Ye, Fang3
  • Cheng, Meng-Li4
  • Feng, Yu1
  • Deng, Yong-Qiang4
  • Zhao, Hui4
  • Wei, Peng1
  • Ge, Jiwan5
  • Gou, Mengting1
  • Li, Xiaoli1
  • Sun, Lin1
  • Cao, Tianshu4
  • Wang, Pengzhi1
  • Zhou, Chao4
  • Zhang, Rongrong4
  • Liang, Peng6
  • Guo, Han7
  • Wang, Xinquan5
  • Qin, Cheng-Feng4
  • Chen, Fang6
  • And 1 more
  • 1 Institute for Immunology and School of Medicine, Tsinghua University, Beijing 100084, China
  • 2 Center for Human Disease Immuno-monitoring, Beijing Friendship Hospital, Beijing 100050, China
  • 3 Department of Hematology, Chui Yang Liu Hospital affiliated to Tsinghua University, Beijing 100022, China
  • 4 Department of Virology, State Key Laboratory of Pathogen and Biosecurity, Institute of Microbiology and Epidemiology, Academy of Military Medical Sciences, Beijing 100071, China
  • 5 School of Life Sciences, Tsinghua University, Beijing 100084, China
  • 6 Department of Cardiology, Chui Yang Liu Hospital affiliated to Tsinghua University, Beijing 100022, China
  • 7 Department of Orthopedics, Chui Yang Liu Hospital affiliated to Tsinghua University, Beijing 100022, China
  • 8 Beijing Key Lab for Immunological Research on Chronic Diseases, Beijing 100084, China
Type
Published Article
Journal
Immunity
Publication Date
May 03, 2020
Identifiers
DOI: 10.1016/j.immuni.2020.04.023
PMCID: PMC7196424
Source
PubMed Central
Keywords
License
Unknown

Abstract

In blood samples from COVID-19 convalescent subjects, Ni et al. have detected SARS-CoV-2-specific humoral and cellular immunity. Most subjects display serum neutralizing activities, which correlate with the numbers of virus-specific T cells.

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