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Detection of p53 gene mutations in human leukemia by PCR-SSCP analysis and direct nucleotide sequencing.

Authors
  • Wang, R
  • Yu, Z
  • Gu, J
  • Li, D
  • Wang, M
  • Cao, Y
Type
Published Article
Journal
Chinese medical journal
Publication Date
Apr 01, 1998
Volume
111
Issue
4
Pages
339–342
Identifiers
PMID: 10374399
Source
Medline
License
Unknown

Abstract

The p53 gene mutations are specifically associated with lymphocytic leukemia. Alternations of the p53 gene may play a certain role in leukemogenesis in some cases of lymphocytic leukemia.

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