Detection and monitoring of trisomy 8 by fluorescence in situ hybridization in acute myeloid leukemia: a multicentric study.
Institute of Hematology, University of Ferrara, Italy.
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It is concluded that FISH was a valuable method in this multicentric study since it showed greater sensitivity than CCA in detecting minor clones with +8, in patients with both normal and abnormal karyotypes. The role of FISH in the cytogenetic follow-up of trisomies in AML patients may be promising.
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The corresponding record at NLM can be accessed at https://www.ncbi.nlm.nih.gov/pubmed/9542319